Kamagra Super is a pharmaceutical product known for addressing erectile dysfunction. This product contains two active compounds: sildenafil 100 mg and dapoxetine 60 mg. These agents work together to enhance erectile function and manage premature ejaculation. Sildenafil, a potent phosphodiesterase type 5 (PDE5) inhibitor, increases blood flow to the penile region. Dapoxetine, a selective serotonin reuptake inhibitor (SSRI), modifies serotonin levels in the brain, enhancing control over ejaculation. This combination ensures improved sexual experience and satisfaction.
Pharmacokinetics
Sildenafil 100 mg exhibits rapid absorption following oral administration. Peak plasma concentrations occur within 30 to 120 minutes. Food can delay absorption, influencing its efficacy. The plasma half-life of sildenafil spans approximately 4 hours, facilitating its effectiveness during short-term use. Metabolized primarily in the liver, sildenafil produces an active metabolite, N-desmethylsildenafil. Both compounds are excreted predominantly through the fecal route.
Dapoxetine 60 mg undergoes swift absorption, reaching peak plasma concentrations in roughly 1 to 2 hours. Its rapid metabolism involves the cytochrome P450 isoenzymes, resulting in inactive metabolites. The plasma half-life of dapoxetine is around 19 hours, contributing to its suitability for on-demand use. Excretion occurs mainly via renal pathways.
Mechanism of Action
The mechanism by which Kamagra Super achieves its effects involves the synergy of its two components. Sildenafil inhibits PDE5, an enzyme responsible for cGMP degradation in the penile tissue. Elevated cGMP levels result in smooth muscle relaxation and enhanced blood flow, vital for achieving and maintaining an erection.
Dapoxetine’s influence on serotonin reuptake modulates the synaptic levels of this neurotransmitter. It delays the ejaculatory reflex, prolonging intravaginal ejaculatory latency. This mechanism ensures control over ejaculation, allowing men to last longer during sexual activity. Together, these processes enhance sexual performance and satisfaction.
Kamagra Super Contraindications
Kamagra Super presents several contraindications due to its pharmacological activity. Individuals with hypersensitivity to sildenafil, dapoxetine, or any excipients should avoid its use. The presence of serious cardiovascular conditions such as severe heart failure, recent myocardial infarction, or unstable angina contraindicates this medication.
Patients with significant liver or kidney impairment should refrain from using Kamagra Super. Co-administration with nitrates, nitric oxide donors, or other PDE5 inhibitors is contraindicated due to the risk of severe hypotension. Dapoxetine contraindications include a history of syncope, bipolar disorder, or significant psychiatric conditions.
Kamagra Super Interactions
Kamagra Super may interact with various pharmaceuticals, necessitating caution. Co-administration with CYP3A4 inhibitors like ketoconazole or ritonavir increases sildenafil plasma concentrations. This may enhance side effects such as headache or dizziness. Caution is advised with CYP2D6 inhibitors like fluoxetine or paroxetine, which affect dapoxetine metabolism.
Concomitant use with alcohol enhances the sedative effects of dapoxetine. It increases the risk of syncope or dizziness. Grapefruit juice can influence sildenafil metabolism, affecting its efficacy. Patients should avoid nitrate medications and certain antihypertensives to prevent severe blood pressure drops.
Effects of Kamagra Super
Kamagra Super improves erectile function and enhances sexual satisfaction by delaying ejaculation. Sildenafil’s action results in a firm, sustainable erection. Dapoxetine allows for better control over ejaculation, increasing sexual enjoyment and confidence.
Common side effects include headaches, dizziness, flushing, and nasal congestion. Gastrointestinal disturbances like nausea or diarrhea may occur. In some cases, visual disturbances such as blurred vision or altered color perception are noted. Syncope is a potential risk, especially with dapoxetine.
Kamagra Super Over The Counter
Kamagra Super is typically not available over the counter. It requires a prescription due to its potential side effects and interactions. In certain regions, regulations may differ, allowing easier access. However, self-medication is not advisable due to health risks.
Consulting a healthcare professional ensures safe usage, considering contraindications and interactions. Obtaining Kamagra Super through reputable channels prevents the risks associated with counterfeit products. Patients should adhere to medical guidance to achieve optimal outcomes.
| Component | Dosage | Function |
|---|---|---|
| Sildenafil | 100 mg | PDE5 Inhibitor |
| Dapoxetine | 60 mg | SSRI |
Kamagra Super offers a reliable solution for men with erectile dysfunction and premature ejaculation. Its dual action addresses both issues, enhancing overall sexual experience. However, careful consideration of contraindications and interactions is crucial. Medical guidance ensures safe and effective use, preventing adverse effects and maximizing benefits. For optimal health and safety, always consult healthcare professionals before use.
- Improves erectile function
- Delays ejaculation
- Enhances sexual satisfaction